This guide introduces beginners to common PED classes for women, their mechanisms, and ways to mitigate unwanted effects. It outlines typical usage lengths and emphasizes post-cycle support with natural supplements rather than traditional drugs like Clomid or Nolvadex. Regular lab monitoring and a solid nutrition-training foundation are stressed for safety and long-term health.
Responsible use of PEDs
Female athletes often struggle to build muscle, enhance definition, and reduce body fat through natural training alone. To achieve faster results, many opt for low-dose, short-cycle PEDs, which can offer significant gains in strength and leanness, though they may also pose risks and side effects.
When used responsibly—by maintaining moderate doses, limiting cycle lengths, and combining with targeted supportive supplements—these substances can enhance strength, lean mass, and leanness, while minimizing side effects.
⚠️ Virilization in women refers to developing male traits from using PEDs, particularly anabolic steroids. Symptoms can include increased body hair growth, a deeper voice, clitoral growth, and menstrual irregularities, all stemming from elevated testosterone levels. Women should exercise caution when using PEDs, as reversing these effects can be difficult or even impossible. Low-end dosage is usually sufficient! These substances are not for beginners!
Anabolic‑androgenic steroids – low‑androgenic options
AAS are the most potent muscle‑builders available, but many of them carry a high risk of virilization in women. Selecting steroids with a low androgenic index and staying at the low end of dosing can give lean‑mass gains and improved definition while minimizing the chance of voice deepening, facial hair growth, or menstrual disruption.
Steroid comparison
| Steroid | Typical female dose* | Main benefits | Common risks | Max cycle length |
|---|---|---|---|---|
| Oxandrolone (anavar) | 5 – 20 mg day | lean‑mass gain, strength, modest fat loss | virilization, liver stress | 8 weeks |
| Stanozolol (winstrol) | 5 – 15 mg day | hard‑cutting, muscle definition | virilization, joint pain, cholesterol rise | 6 weeks |
| Methenolone (primobolan, oral) | 25 – 50 mg day | mild bulking or cutting, low androgenic activity | mild virilization, oral liver strain | 8 weeks |
*start at the low end; only increase after two consecutive labs stay normal. Low end dosage is usually sufficient! ⚠️
How to reduce side‑effects
Anti‑virilization stack – maca root 500 mg day, ashwagandha 300 mg day, dim 150 mg day. liver protection – milk thistle 300 mg day or n‑acetylcysteine (nac) 600 mg day (especially for oral steroids). lipid support – omega‑3 fish oil 2 g day and niacin 50 mg day. lab checks – liver enzymes, lipid panel, lh/fsh, estradiol every 3‑4 weeks.
Post‑cycle support (no classic pct)
Women’s hormone axis usually recovers on its own. focus on natural balance: maca root 500 mg day, ashwagandha 300 mg day, dim 150 mg day, magnesium 400 mg day, vitamin d3 2000 IU day. keep protein ≥ 1.6 g kg⁻¹ and avoid extreme dieting for at least 4 weeks to lock in gains. ✅
Start at the lowest dose and only raise it after two consecutive lab panels show normal liver enzymes, lipids, and hormone levels; protect the liver with milk‑thistle or NAC and keep virilization in check by taking a daily anti‑virilization stack of maca, ashwagandha and DIM.
Mesterolone – moderate‑risk steroid
Mesterolone is an oral androgen that binds sex‑hormone‑binding globulin (SHBG), raising free testosterone. This modest boost can improve mood, libido, and add a small amount of lean mass, but the oral androgenic nature raises the chance of virilization compared with the low‑androgenic steroids above.
| Property | Details |
|---|---|
| typical dose* | 25 – 50 mg day (oral) |
| main action | increases free testosterone → modest muscle gain, better libido |
| why moderate‑risk | oral androgen → higher virilization chance; does not aromatize, so estrogen‑related issues are minimal, but liver stress is present. |
| common risks | voice deepening, facial/body hair growth, menstrual changes, mild liver‑enzyme rise |
| max cycle length | 6‑8 weeks (stay at the low end of the dose) |
| lab checks | every 2 weeks: total testosterone, lh/fsh, alt/ast, lipid panel |
| when to stop | any sign of virilization or liver enzymes > 2 × uln |
*low end dosage is usually sufficient! ⚠️
Side‑effect mitigation
Anti‑virilization – maca 500 mg, ashwagandha 300 mg, dim 150 mg. liver protection – milk‑thistle 300 mg or nac 600 mg. lipid support – omega‑3 2 g, niacin 50 mg. ⚖️
Post‑cycle support
Continue the anti‑virilization & liver‑protective stack for 4 weeks; no classic pct needed.
Run liver‑function tests every two weeks and stop the cycle if ALT or AST rise above 2 × the upper limit of normal; because mesterolone does not aromatize, focus on omega‑3 and niacin for lipid balance while maintaining a modest protein intake (≥ 1.6 g kg⁻¹) to support muscle growth.
Microdosing testosterone
Microdosing testosterone can provide women with benefits such as improved muscle mass, strength, and recovery, making it a popular choice among athletes. However, careful dosage management is essential to minimize potential side effects.
| Form | Dosage Range | Frequency | Benefits | Risks |
|---|---|---|---|---|
| Injectable Testosterone | 10–20 mg | Every 5-7 days | Enhanced muscle strength, increased recovery | Potential virilization, mood changes |
| Testosterone Cream | 5–10 mg | Daily | Increased endurance, improved body composition | Skin irritation, menstrual irregularities |
| Testosterone Patch | 5–10 mg | Daily | Consistent hormone delivery, convenience | Localized skin reactions, hormonal imbalances |
Key benefits
- Enhanced Performance: Increased strength and stamina can lead to improved training outcomes.
- Better Recovery: Microdoses may aid in quicker recovery between workouts, reducing fatigue.
- Reduced Side Effects: Lowered risk of androgenic effects compared to higher dosages, making it more suitable for women.
Monitoring and precautions
- Regular blood tests are critical to monitor hormone levels and overall health.
- Consult healthcare providers to adjust dosages based on individual responses.
- Pay attention to body changes and side effects to make timely adjustments.
How to reduce side‑effects
Anti‑virilization stack – maca root 500 mg day, ashwagandha 300 mg day, dim 150 mg day. liver protection – milk thistle 300 mg day or n‑acetylcysteine (nac) 600 mg day (especially for oral steroids). lipid support – omega‑3 fish oil 2 g day and niacin 50 mg day. lab checks – liver enzymes, lipid panel, lh/fsh, estradiol every 3‑4 weeks.
Post‑cycle support (no classic pct)
Women’s hormone axis usually recovers on its own. focus on natural balance: maca root 500 mg day, ashwagandha 300 mg day, dim 150 mg day, magnesium 400 mg day, vitamin d3 2000 IU day. keep protein ≥ 1.6 g kg⁻¹ and avoid extreme dieting for at least 4 weeks to lock in gains. ✅
Microdosing testosterone can be a valuable tool for women in bodybuilding, allowing for enhanced physical performance with lowered risk of side effects. Starting doses typically range from 5-10 per week for injectables or 5–10 mg daily for creams. Always prioritize regular monitoring and professional guidance to ensure safe and effective use.
Anabolic‑androgenic steroids – high‑androgenic options
High‑androgenic AAS deliver stronger anabolic signals but carry a markedly higher risk of virilization in women. They are generally reserved for athletes who accept these risks for rapid muscle‑mass gains or who plan to use very short “burst” cycles with aggressive anti‑virilization protocols.
| Steroid | Low-Dose Range & Frequency* | Primary Benefit | Anti-Virilization / Precautions | Max Cycle |
|---|---|---|---|---|
| Testosterone Enanthate/Cypionate | 25–50 mg i.m. every 5 days (~25–75 mg/week) | Strong lean-mass and strength gains | Spironolactone 50 mg/day; finasteride 0.5 mg/day; liver protectors (milk thistle 300 mg/day or NAC 600 mg/day) | 4 weeks |
| Nandrolone Decanoate | 25–50 mg i.m. every 7 days (~25–100 mg/week) | Muscle hypertrophy and joint-pain relief | Spironolactone 50 mg/day; monitor voice/hair; milk thistle 300 mg/day | 6 weeks |
| Injectable Methenolone | 50–100 mg i.m. every 7 days (~50–200 mg/week) | Lean muscle retention, improved muscle hardness | Spironolactone may help; monitor for side effects | 6-8 weeks |
| Boldenone Undecylenate | 50–100 mg i.m. every 7 days (~50–200 mg/week) | Steady muscle growth, modest strength increase | Spironolactone 50 mg/day; if edema appears add anastrozole 0.25 mg/day; milk thistle 300 mg/day | 6 weeks |
| Trenbolone Acetate (research-only) | 12.5–25 mg i.m. every 3 days (~30–60 mg/week) | Very rapid muscle and strength gains | Spironolactone 50 mg/day + finasteride 0.5 mg/day; strict weekly self-check for voice/hair; stop after 2 weeks if issues | 2 weeks |
| Drostanolone Propionate | 10–20 mg i.m. every 3 days (~20–40 mg/week) | Lean-mass gain with relatively low androgenic effect | Spironolactone 50 mg/day; liver protectors (NAC 600 mg/day) | 4 weeks |
*start at the low end; only increase after two consecutive labs remain within normal limits. Low-end dosage is usually sufficient! ⚠️
Mitigating the higher virilization risk
| Mitigation approach | How it works | Practical dosing (under medical supervision) |
|---|---|---|
| Spironolactone (anti‑androgen) | Blocks androgen receptors and reduces DHT activity, limiting hair growth and voice changes. | 50 mg once daily (may increase to 100 mg if needed). |
| Finasteride (5‑α‑reductase inhibitor) | Prevents conversion of testosterone to the more potent DHT, which is a key driver of hirsutism and vocal cord thickening. | 0.5 mg once daily. |
| Flutamide (pure anti‑androgen) | Directly competes with androgens at the receptor level; useful when spironolactone alone is insufficient. | 250 mg once daily (prescribed). |
| Aromatase inhibitor (if estrogen‑related water retention appears) | Reduces conversion of testosterone to estradiol, helping control fluid retention and blood‑pressure spikes. | Anastrozole 0.25 mg once daily (only if edema or elevated estradiol is observed). |
| Liver protectors | Mitigate hepatic stress from oral AAS or high‑dose injectable formulations. | Milk‑thistle extract 300 mg day or N‑acetylcysteine 600 mg day. |
| Lipid & cardiovascular support | Counteract the adverse lipid profile often seen with high‑androgenic steroids. | Omega‑3 fish oil 2 g day; niacin 50 mg day (extended‑release). |
| Regular self‑assessment | Early detection of virilization allows prompt dose adjustment or cycle termination. | Weekly check of voice pitch, facial/body hair growth, and menstrual regularity; stop the cycle if any change is noted. |
Practical implementation for low‑dose injectable steroids
- Pre‑cycle (‑2 to ‑3 days)
- Begin spironolactone 50 mg day + finasteride 0.5 mg day.
- Start liver protectors (milk‑thistle 300 mg day or NAC 600 mg day).
- During the cycle
- Keep the anti‑androgen stack daily for the whole steroid period.
- Continue liver‑protective supplement every day.
- Lab checks (ALT/AST, lipid panel, LH/FSH, estradiol, total testosterone) every 2 weeks.
- Weekly self‑assessment: note any changes in voice pitch, facial/body hair growth, or menstrual pattern.
- If labs show ALT/AST > 2 × ULN
- Reduce or stop spironolactone/finasteride immediately and re‑evaluate labs in 1 week.
- If virilization signs appear
- Cease the steroid right away.
- Continue spironolactone + finasteride for additional 4 weeks.
- Maintain liver protectors and repeat labs every 2 weeks until values normalize.
- Post‑cycle (first 2 weeks)
- Keep the anti‑androgen stack unchanged for at least 2 weeks after the last steroid injection.
- Add maca root 500 mg day + zinc 30 mg day for 4 weeks to support HPG‑axis recovery.
- Maintain protein intake ≥ 1.8 g kg⁻¹ and a balanced diet to preserve lean mass.
Following this schedule helps establish receptor blockade before exposure, limits androgenic side‑effects throughout the cycle, and supports safe hormonal rebound afterward.
Post‑cycle support (high‑androgenic cycles)
- Hormone rebound – continue spironolactone or flutamide for 2‑3 weeks after the last steroid dose.
- LH/FSH stimulation – maca root 500 mg day + zinc 30 mg day for 4 weeks to aid axis recovery.
- Liver & lipid care – maintain milk‑thistle/NAC and omega‑3 throughout the PCT period.
- Protein & caloric intake – keep protein ≥ 1.8 g kg⁻¹ and avoid severe caloric deficits for at least 4 weeks to preserve newly‑gained muscle.
Lab monitoring: check liver enzymes, lipid panel, and hormone panel (LH, FSH, estradiol, total testosterone) every 2 weeks during the cycle and weekly during the first two weeks of PCT. Stop the cycle if any value exceeds 2 × ULN or if virilization signs appear.
Safety note: High‑androgenic steroids are especially likely to be prohibited under WADA rules and many national regulations. Use only with a valid prescription, medical supervision, and a clear understanding of the legal and competitive ramifications.
Human growth hormone (HGH)
HGH is prized for its ability to speed muscle repair, improve joint health, and enhance skin quality without any androgenic side‑effects. Because it works systemically, the primary concerns are metabolic—especially insulin sensitivity—and occasional fluid retention.
Basics
- Dose: Typically, 2 to 4 IU per day via subcutaneous injection. Starting with 1 IU per day is recommended, gradually increasing based on individual response.
- Why women like it: Faster muscle repair, joint health, smoother skin, and no virilization.
- Risks: Joint pain, carpal tunnel, possible insulin resistance, peripheral edema.
- A beginner cycle lasts 12 weeks, followed by a 2-week off-phase before restarting. More advanced users may extend HGH usage in cycles of 3 to 6 months for enhanced results.
Blunting side‑effects
Insulin‑sensitivity aid – berberine 500 mg day or α‑lipoic acid 300 mg day. joint comfort – omega‑3 2 g day, glucosamine 1500 mg day + chondroitin 1200 mg day. monitoring – fasting glucose, igf‑1, cbc monthly. 🩺
Post‑cycle support
Continue the insulin‑sensitivity stack for 2‑3 weeks after stopping hgh and keep protein ≥ 1.6 g kg⁻¹ to preserve lean mass.
Monitor fasting glucose, IGF‑1 and CBC monthly, and use berberine or α‑lipoic acid daily to preserve insulin sensitivity and reduce the risk of glucose spikes.
Selective androgen receptor modulators (SARMS)
SARMs bind to androgen receptors in muscle and bone but cause far less activation of androgenic tissues such as the skin and hair follicles. This makes them attractive for women who want muscle growth and fat loss with a lower risk of virilization, though they can still modestly suppress endogenous testosterone.
Sarm comparison
| SARM | Dose (women) | Primary use | Notable side‑effects | Max cycle length |
|---|---|---|---|---|
| ostarine (mk‑2866) | 10 – 15 mg day | muscle gain, mild fat loss | possible testosterone suppression | 12 weeks |
| andarine (s4) | 25 – 50 mg day | strength, lean mass | night‑vision changes, mild suppression | 8 weeks |
| cardarine (gw‑501516) | 10 – 20 mg day | endurance, fat oxidation (research‑only) | limited long‑term safety data | 12 weeks |
Managing side‑effects
Testosterone support (if needed) – maca 500 mg day + zinc 30 mg day. vision protection for andarine – lutein/zeaxanthin 10 mg day. liver safety – milk thistle or nac as with aaas. 👀
Post‑cycle support
Run a mid‑cycle hormone panel. if testosterone falls below the lower normal range, keep the maca‑zinc blend for 2‑3 weeks, then re‑test. no clomid/nolvadex required. ✅
Keep the dose at the lower end of the recommended range, run a mid‑cycle hormone panel to catch any testosterone suppression, and mitigate specific side effects—such as night‑vision changes with andarine—by adding lutein/zeaxanthin, while supporting liver health with milk‑thistle or NAC.
Peptides – recovery, anti‑aging & beauty
Peptides are short chains of amino acids that target specific biological pathways, such as tissue repair, growth‑hormone release, or collagen synthesis. They are generally well‑tolerated and can complement a training program by speeding recovery, improving joint health, or enhancing skin quality.
Peptide comparison
| Peptide | Typical dose | Main action | Common concerns | Typical cycle |
|---|---|---|---|---|
| BPC‑157 | 200 µg/day (s.c.) | Tendon, ligament, gut healing | Injection‑site irritation | 8–12 weeks |
| Tesamorelin | 2 mg/day (s.c.) | GH release; visceral‑fat reduction | Possible glucose rise | 12 weeks |
| CJC‑1295 + DAC | 100–200 µg every 2–3 days (s.c.) | Sustained GH elevation; recovery | Water retention | 12 weeks |
| GHK‑Cu | 50–200 µg/day (s.c. or topical) | Collagen boost; improved skin elasticity | Minimal systemic effects | 12 weeks |
| Melanotan‑2 (MT2) | 0.5–1 mg/day (s.c.) | Tanning; modest fat loss; libido boost | Nausea; blood‑pressure rise | 8 weeks |
| Thymosin α1 | 1.6 mg/day (s.c.) | Immune modulation; potential anti‑aging effects | Rare injection reactions | 12 weeks |
| Epithalon | 10 mg/day (oral) | Telomere maintenance; improved sleep quality | Limited human data | 12 weeks |
| NAD⁺ precursors (NR/NMN) | 250–500 mg/day (oral) | Supports cellular energy and DNA repair | Generally well‑tolerated | Indefinite (maintenance) |
Side‑effect mitigation
Tesamorelin (glucose) – berberine 500 mg day with meals. cjc‑1295 (water retention) – moderate sodium, dandelion root 500 mg day if edema appears. general injection irritation – rotate sites, use sterile technique, apply topical antiseptic.
Post‑cycle support
Peptide cycles end naturally as the compound clears. continue high‑protein foods and collagen‑rich sources (bone broth, fish skin) for 2‑3 weeks to lock in tissue‑repair gains.
Rotate injection sites and use sterile technique to avoid irritation, address glucose elevations from tesamorelin with berberine, and counter water retention from CJC‑1295 by moderating sodium intake and adding dandelion root if edema appears.
Weight‑loss medications & glp‑1 / dual‑agonists
Modern GLP‑1 and dual‑agonist drugs provide powerful appetite suppression and metabolic benefits with a safety profile far better than older stimulants. Clenbuterol, a β2‑agonist, remains a rapid‑fat‑loss option for very short bursts.
Agent comparison
| Agent | Dose | Mechanism | Key Benefits | Typical Use | Max Duration |
|---|---|---|---|---|---|
| Clenbuterol | 20-40 µg/day (split) | β2-agonist ↑ metabolism, mild anabolic effect | Fast fat loss, slight muscle-preserving effect | 2-4 weeks (no-stack >4 weeks) | 4 weeks |
| Phentermine | 15-30 mg/day (oral) | Sympathomimetic appetite suppressant | Quick appetite drop | 12-24 weeks, under doctor’s care | 24 weeks |
| Liraglutide (Saxenda) | 0.6 → 3 mg/day (sc) | GLP-1 → satiety | Moderate weight loss, glucose control | Up to 24 weeks | 24 weeks |
| Semaglutide | 0.5 → 2.4 mg/week (sc) | GLP-1 → strong satiety | 10-15% body weight loss | Ongoing; labs quarterly | 12-18 months (with breaks) |
| Tirzepatide | 5 → 15 mg/week (sc) | GLP-1 + GIP → powerful satiety, insulin sensitization | Up to 20% weight loss | 6-12 months, then pause | 12 months |
| Retatrutide | 4 → 8 mg/week (sc) | GLP-1 + glucagon → appetite ↓, metabolic boost | Strong weight loss, better lipids | 6 months | 12 months |
| CagriLintide | 2.4 mg/week (sc) | Amylin analog → slower gastric emptying, satiety | Synergizes with GLP-1 agents | 6 months | 12 months |
| Mazdutide | 2.4 → 4.8 mg/week (sc) | GLP-1 + GIP → satiety, metabolic health | Similar to tirzepatide | 6 months | 12 months |
| Orlistat (Alli) | 60 mg tid with meals (oral) | Fat absorption blocker | Reduces caloric absorption | 12-24 weeks; supplement fat-soluble vitamins | 24 weeks |
| T3 (Liothyronine) | 25-75 µg/day (orally) | Increases metabolic rate, enhances protein synthesis | Rapid weight loss, increased energy levels | Short-term for acute weight loss | 8-12 weeks |
| T4 (Levothyroxine) | 50-200 µg/day (orally) | Regulates metabolism, promotes energy production | Improved metabolic rate, potential weight maintenance | Long-term management of hypothyroidism | Ongoing under doctor’s supervision |
Blunting side‑effects
Nausea (glp‑1 agents) – start at the lowest dose, titrate slowly; ginger root 500 mg day or peppermint tea before each dose. blood‑pressure rise (phentermine) – co‑q10 200 mg day and magnesium 400 mg day. glucose spikes (tesamorelin, some glp‑1 combos) – berberine 500 mg day or α‑lipoic acid 300 mg day.
Post‑cycle support
When stopping a glp‑1 or dual‑agonist, taper over 2‑3 weeks to avoid rebound hunger. keep the ginger/peppermint regimen for a week, maintain high protein intake, and continue the magnesium‑co‑q10 combo for blood‑pressure stability. 🛑
Begin each agent at the lowest dose and titrate slowly (especially GLP‑1 drugs) to minimize nausea, supplement with ginger or peppermint for gastrointestinal comfort, and monitor blood pressure when using stimulants like phentermine or clenbuterol, adding CoQ10 and magnesium if pressures rise.
Sexual‑support compounds for women
Sexual health is a core component of overall performance and well‑being. The following agents improve genital blood flow, stimulate melanocortin receptors, or balance neurotransmitters without the hormonal suppression seen with many steroids.
Compound comparison
| Compound | Typical dose & administration | Primary effect | Max duration |
|---|---|---|---|
| Avanafil | 50–100 mg oral, ~30 min before activity | Improves genital blood flow (PDE5) | As needed; ≤6 months continuous |
| PT‑141 (Bremelanotide) | 1.25–2.5 mg s.c. or intranasal, as needed | Boosts sexual desire | As needed; ≤6 months continuous |
| Flibanserin | 100 mg oral, nightly | Increases libido (FDA‑approved) | Indefinite with physician monitoring |
| L‑arginine + Pycnogenol | 3 g L‑arginine + 150 mg Pycnogenol oral daily | Enhances nitric‑oxide vasodilation | Indefinite |
| Vardenafil | 10 mg oral, as needed | PDE5 inhibition, improves arousal | As needed; ≤6 months continuous |
Keeping side‑effects low
Monitor blood pressure when using pde5 inhibitors (avanafil, vardenafil). avoid high‑dose melatonin with pt‑141, as it can blunt the central effect. stay well‑hydrated to support nitric‑oxide pathways.
Post‑cycle support
No hormonal pct is needed. continue magnesium + vitamin d3 for overall hormonal stability and ashwagandha for stress‑related libido fluctuations. 🌙
Track blood pressure regularly when taking PDE‑5 inhibitors (avanafil, vardenafil), stay well‑hydrated to support nitric‑oxide pathways, and avoid high‑dose melatonin with PT‑141 to prevent blunting of its central effects.
Monitoring & safety
Regular lab work is essential, even with low‑dose cycles.
| Test | Frequency | What to watch |
|---|---|---|
| cbc | every 4 weeks | anemia, leukopenia (especially with oral aaas) |
| cmp (liver, electrolytes) | every 4 weeks | alt/ast rise, bilirubin |
| lipid panel | every 4 weeks | hdl drop, ldl rise |
| hormone panel (lh, fsh, estradiol, total testosterone) | every 3‑4 weeks | suppression of hpg axis |
| fasting glucose / hbA1c | every 4 weeks (more often with gh‑releasing peptides) | rising glucose |
| ecg | baseline and after any β2‑agonist >2 weeks | qt changes, arrhythmias |
| thyroid panel | every 8 weeks (if using thyroid‑modulating peptides) | tsh, free t4, free t3 |
stop the cycle if any value exceeds 2 × uln or falls below ½ × lln, then reassess dosing. 🚨
Psychological tips
Mood swings (common with mesterolone or high‑dose hgh) – magnesium glycinate 400 mg nightly + b‑complex. insomnia (clenbuterol, sarms) – melatonin 3 mg 30 min before bed. body‑image concerns – consider talking to a sports‑psychology professional during rapid composition changes.
Legal & ethical reminder
Most aas, hgh, and many sarms are prescription‑only in most countries. using them without a valid prescription may be illegal. competitive athletes should check the current world anti‑doping agency (wada) list, as many of these substances are prohibited in sanctioned events. always obtain a medical clearance and keep a written health‑screening record before starting any cycle.
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